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摘要： Objective To explore the situation and trend of drug use in the treatment of hypertension in outpatient department of a hospital, and to provide reference for clinical rational drug use. Methods The data of 833 outpatients with hypertension in a hospital from July to December in 2020 were retrospectively analyzed. Results and Conclusion Among the 833 cases, calcium channel blocker (CCB) was the most frequently used drug (38.54%), followed by angiotensin receptor blocker (ARB) (13.81%), β-receptor blockers (β-RB) (10.44%), angiotensin-converting enzyme inhibitor (ACEI) (5.52%), and diuretics (0.72%). The combination rate was 37.09% (including single-pill combination, SPC). The highest rate was the combination of two drugs (28.21%), followed by the combination of three drugs (8.64%) and four drugs (1.20%). The DDDs and DDC of SPC were the highest among the six kinds of drugs. The use of antihypertensive drugs in outpatient department of the hospital is in line with the medication guidelines, but a small number of drugs are used irrationally, which needs further supervision and management.
