亚洲社会药学 ›› 2022, Vol. 17 ›› Issue (4): 343-350.

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Economic Evaluation of Gastroscopy for Detecting Gastric Cancer in Chinese Natural Population

  

  • 出版日期:2022-12-26 发布日期:2022-12-26

Economic Evaluation of Gastroscopy for Detecting Gastric Cancer in Chinese Natural Population

  • Online:2022-12-26 Published:2022-12-26

摘要:

Objective To evaluate the economy of detecting gastric cancer by electronic gastroscope in Chinese natural population of different ages and genders. Methods A Markov model was constructed for the population, including both men and women of different ages. The model cycle was one year and the simulation time was 60 years. The cost-effectiveness of electronic gastroscopy in detecting gastric cancer of general population in China was analyzed from the perspective of the whole society, and the stability of the results was verified by sensitivity analysis. Results and Conclusion For the general population, the incremental cost-effectiveness ratio (ICER) of gastric cancer screening from the age of 50 is 50 143 yuan/QALY (quality-adjusted life-year), which is less than two times of per capita gross domestic product (GDP) compared with the screening from the age of 55. For men who start gastric cancer screening at the age of 50, the ICER is 38 525 yuan/QALY, which is less than two times of per capita GDP, and it is economical. For women who start the screening from the age of 55, the ICER is 47 814 yuan/QALY, which is less than two times of per capita GDP, so it is economical. The results of sensitivity analysis are consistent with the conclusions of basic analysis, and the results of basic analysis are stable. For the general population, it is more economical to start gastric cancer screening from the age of 50, while for men and women, it is more economical to start gastric cancer screening from the age of 50 and 55, respectively.

关键词:

Abstract: Objective To evaluate the economy of detecting gastric cancer by electronic gastroscope in Chinese natural population of different ages and genders. Methods A Markov model was constructed for the population, including both men and women of different ages. The model cycle was one year and the simulation time was 60 years. The cost-effectiveness of electronic gastroscopy in detecting gastric cancer of general population in China was analyzed from the perspective of the whole society, and the stability of the results was verified by sensitivity analysis. Results and Conclusion For the general population, the incremental cost-effectiveness ratio (ICER) of gastric cancer screening from the age of 50 is 50 143 yuan/QALY (quality-adjusted life-year), which is less than two times of per capita gross domestic product (GDP) compared with the screening from the age of 55. For men who start gastric cancer screening at the age of 50, the ICER is 38 525 yuan/QALY, which is less than two times of per capita GDP, and it is economical. For women who start the screening from the age of 55, the ICER is 47 814 yuan/QALY, which is less than two times of per capita GDP, so it is economical. The results of sensitivity analysis are consistent with the conclusions of basic analysis, and the results of basic analysis are stable. For the general population, it is more economical to start gastric cancer screening from the age of 50, while for men and women, it is more economical to start gastric cancer screening from the age of 50 and 55, respectively.

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