Asian Journal Of Social Pharmacy

Abstract: Objective To explore the rules and characteristics of the adverse drug reactions (ADRs) of three Chinese patent medicines and three herbal formulas for the treatment of COVID-19, and to provide a reference for clinical safe medication. Methods The cases and ADR reports of the three Chinese patent medicines and three herbal formulas in PubMed, Web of Science, Springer Link, CNKI, Wanfang and VIP database were retrieved from December 2019 to May 2021. Then we extracted and analyzed the effective information included in the literature. Results and Conclusion According to the pre-developed retrieval plan, a total of 136 documents were obtained, and a total of 6 documents met the inclusion criteria finally. 553 patients used three Chinese patent medicines and three herbal formulas, and there were 133 cases of adverse reactions. The adverse reactions of patients taking the three Chinese patent medicines and three herbal formulas can all be explained under the theory of traditional Chinese medicine, and the adverse reactions can be eliminated by adding or subtracting the flavor of the medicine or stopping the medicine.

Key words: